Peyote triggers an increase in body temperature and heart rate, heavy sweating, muscle weakness, nausea and vomiting, and lack of coordination.
Hallucinations are common among users of peyote, as is a feeling of euphoria. In some cases, high doses or a poor response to the drug can result in feelings of extreme anxiety, panic, or fear.
Regular use of peyote, or mescaline, can lead to increased tolerance in less than a week. Additionally, medical emergency caused by use of the drug may occur as well. In some cases, addiction can develop.