Call us today

(973) 862 4820
Menu close
Help Available 24/7

Our Centers

  • Take the First Step in Las Vegas

    Desert Hope is a beautiful oasis with modern charm located in Las Vegas, Nevada. We provide all levels of care from detox, in-patient, outpatient and sober living.

    Visit Desert Hope Treatment Center Visit Desert Hope Treatment Center
  • A New Life Awaits

    Start your recovery at our spa-like facility in the Dallas-Ft. Worth area. Holistic therapies, chef-prepared meals, and LGBTQ+ support are among the many features of our premier drug and alcohol treatment program.

    Visit Greenhouse Treatment Center Visit Greenhouse Treatment Center
  • The Best Place to Recover in Orange County

    Laguna Treatment Hospital is located in Orange County, CA. The first Chemical Dependency Recovery Hospital in the OC, we offer safe medical detox, mental health support, and wellness programs.

    Visit Laguna Treatment Hospital Visit Laguna Treatment Hospital
  • Start Recovery at Our Southern Resort

    Take a step back from your life and get the help you need at our premier drug and alcohol addiction center. Nestled in the countryside 1.5 hours from Memphis, Oxford gives you the support you need in a calm and beautiful setting.

    Visit Oxford Treatment Center Visit Oxford Treatment Center
  • Recovery Forecast includes Tropical Weather

    Your recovery can start at either of two premier drug and alcohol treatment facilities in the Greater Miami area - Fort Lauderdale and Hollywood, FL. Our specialties include treatment for veterans and first responders.

    Visit Recovery First Treatment Center Visit Recovery First Treatment Center
  • Sunny Florida Welcomes You

    Retreat to the sunny climate of Tampa, Florida for a stay at the gold standard of treatment facilities. We offer customized care plans to help you on your recovery journey.

    Visit River Oaks Treatment Center Visit River Oaks Treatment Center
  • Helping New Englanders Find Recovery for Over 30 years

    Escape to the countryside to recovery in New Jersey’s premier drug rehab & treatment center. Located only an hour from New York City.

    Visit Sunrise House Treatment Center Visit Sunrise House Treatment Center

Who Is Organon?

Organon was founded by Dr. Saal van Zwanenberg in Oss, Netherlands, in the early 1920s as a pharmaceutical company. Today, the company manufactures medications in the fields of fertility, gynecology, neuroscience, and anesthesia.

As a Dutch company, Organon began with strong ties to the University of Amsterdam and a professor of pharmacology there, Dr. Ernst Laqueur. As one of the founders, Dr. Laqueur helped to foster collaboration between the university and the pharmaceutical company, the journal Gewina publishes.
Organon has a storied history of acquisitions and sales. Today, it is a subsidiary of Merck (known outside of the US and Canada as MSD & Co.), which is headquartered in Kenilworth, New Jersey. Merck is a $40 billion global healthcare giant that manufactures and distributes vaccines, biologic therapies, prescription medications, and animal health products.

Organon Medications

Organon is known for developing and marketing several oral contraceptives (Mercilon, Marvelon, and the mini-pill Cerazette) and the only vaginal-ring contraceptive, NuvaRing. Organon also produces hormone replacement, or hormone stimulating, therapy medications for fertility, including Pregnyl (chorionic gonadotropin), Orgalutran (ganirelix), and Puregon (follitropin beta). Hormone replacement therapy medications may be used to treat symptoms of menopause and include medications like Livial (tibolone) and Ovestin (oestriol). The testosterone replacement anabolic steroid Andriol (testosterone undecanoate) for men who do not produce enough testosterone on their own.

Organon makes medications for anesthesia like Esmeron (rocuronium bromide) and Norcuron (vecuronium). Organon also manufactures the antidepressant medication Remeron (mirtazapine) and Remeron SolTab, which are orally disintegrating tablets.

Organon’s Historical Timeline

A general timeline of some of the most significant points in the history of Organon follows:

  • 1923: The company was founded as Zwanenberg-Organon and first produced insulin for the treatment of diabetes.
  • 1930s: Organon began producing oestrogens and moved into the field of hormonal contraceptives.
  • 1948: The company acquires the Newhouse research site in Scotland, United Kingdom, to be named Koninklijke Zwanenberg-Organon, or KZO.
  • 1953: Organon starts producing cortisone, a corticosteroid hormone used to decrease inflammation that is typically injected into soft tissue or joints.
  • 1969: KZO merges with AKU, a fibre producer, to become AKZO, which later morphs into Akzo Nobel. Organon becomes the healthcare subsidiary of Akzo Nobel and moves it headquarters to New Jersey.
  • 2007: Akzo Nobel sells the Organon Biosciences unit to Schering-Plough, an American pharmaceutical company, for $14.4 billion, The New York Times In doing so, Akzo moves away from pharmaceuticals in order to focus more on their chemical products as Organon had been dragging behind the industry averages. The sale give Schering-Plough access to Organon’s birth control pill Marvelon as well as several experimental drugs, such as sugammadex (Bridion) for general anesthesia and asenapine (Saphris) for schizophrenia treatment (now marketed for acute manic symptoms associated with bipolar I disorder).
  • 2009: Shering-Plough, and thus Organon, merge with the German pharmaceutical company MSD & Co., or Merck. Within Merck, Organon handles the development of medications for hormone replacement therapy, contraception, anesthesia, and psychiatry.
  • 2013: Merck sells off a legacy Organon site in Oss, Netherlands, to Aspen Pharmacare, triggering fears of job cuts for Organon’s research and development (R&D) and manufacturing employees, the journal FiercePharma
  • 2014: Merck and Organon face a lawsuit for Medicare fraud involving the antidepressant drug Remeron (mirtazapine).

Remeron Scandal

In 2014, Organon USA, Inc. was ordered to pay $31 million in claims after lawsuits alleged that the company defrauded state Medicare programs when they marketed the antidepressant drug Remeron to nursing home pharmacies, Reuters publishes. Claims stated that Organon offered these pharmacies a discounted price for Remeron and then billed Medicare for the full price, potentially as part of an illegal kickback plot that gave the company a competitive edge over other pharmaceutical companies that were marketing similar products at a higher price. Organon was also accused of promoting Remeron for off-label use to treat children and adolescents, although this was not proven.

Remeron is an atypical and tetracyclic antidepressant that is believed to boost the presence of serotonin and noradrenergic activity to enhance and stabilize moods. Conversely, it may also increase suicidal thoughts and actions, particularly in young adults, adolescents, and children.

When used long-term, it may lead to significant withdrawal symptoms when the drug is discontinued. The medication guide published by Merck warns that suddenly stopping Remeron can cause dizziness, headache, sweating, agitation, sleep issues, shaking, anxiety, nausea, vomiting, fatigue, confusion, and tingling sensations. Remeron may then cause physical and emotional dependence if the drug is used long-term or if it is misused and used without a necessary and legitimate prescription. It is, however, generally considered safer and associated with fewer side effects than many other antidepressant medications.

Remeron and Addiction

Antidepressant drugs can increase pleasure and reduce anxiety; therefore, they may be abused recreationally. They may also be used after a prescription has run out, in excess of a necessary prescription, or used after the drug is no longer medically needed. The negative side effects of stopping Remeron can make a person want to keep taking the drug even if it isn’t needed. Individuals may lose their ability to control their dosage of the drug and take it more often and in higher amounts than intended. People may doctor shop, or seek prescriptions from multiple doctors; exaggerate mental health symptoms; ask for or take prescription medications from friends or family members; buy the medications illegally; or steal the drugs in order to keep them on hand.

Remeron is generally considered to have a fairly low abuse and addictive potential, however, and it is even used on an off-label basis to treat addiction sometimes. When used as directed by a medical professional, Remeron may help to reduce drug cravings, enhance abstinence, and improve moods during addiction treatment for opioids, alcohol, methamphetamines, and cocaine, among other substances of abuse. Studies on current methamphetamine users published by the journal Archives of General Psychiatry showed that mirtazapine reduced cravings and use of methamphetamine in individuals who were receiving concurrent counseling for substance abuse.

While Remeron is used in conjunction with therapeutic methods and may have benefits in such a capacity, it is not currently FDA-approved for use in treating addictive disorders.

Return To Pharmaceutical Industry Overview